Recent breakthroughs in health and wellness?

Some of the biggest recent health advances are less about miracle cures and more about treating conditions that were difficult to manage. A few developments from the past several years stand out:

• New obesity medicines: GLP-1 and related medicines such as semaglutide and tirzepatide have made substantial weight loss possible for many patients. Research has also shown benefits beyond weight management, though these medicines require medical supervision and may not suit everyone.
• Gene-editing treatment: Casgevy became the first approved treatment using CRISPR gene editing. It offers some people with sickle cell disease a chance at long-term relief, but treatment is intensive, expensive, and available only to eligible patients.
• Alzheimer’s drugs: Lecanemab and donanemab can slow cognitive decline for some people in the early stages of Alzheimer’s. They do not reverse the disease, and their risks and monitoring requirements mean they are not suitable for everyone.
• Personalized cancer vaccines: Trials are testing vaccines designed around an individual patient’s tumor. The results are promising in some cancers, but these vaccines are still under study—not routine treatment.

The common thread is more targeted care, with benefits that depend on the person and the condition. If you’re considering a new treatment, a clinician can help weigh the evidence, side effects, and access in your situation.